Rapid method for the direct determination of inorganic iodine in plasma using ion-exchange chromatography and the Sandell and Kolthoff reaction
- 1 January 1987
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in The Analyst
- Vol. 112 (6) , 875-878
- https://doi.org/10.1039/an9871200875
Abstract
A simple and rapid method for the determination of inorganic iodine in plasma is described. The iodide fraction is separated by means of protein precipitation with ethanol and cation-exchange chromatography. The destruction of the eluted organic matter is carried out by alkaline ashing prior to determination by the Sandell and Kolthoff reaction. Inorganic iodine in plasma at a concentration as low as 3 µg l–1 can be detected in a sample of 0.5 ml.Keywords
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