The D9N, N291S and S447X variants in the lipoprotein lipase (LPL) gene are not associated with Type III Hyperlipidemia
Open Access
- 29 August 2007
- journal article
- Published by Springer Nature in BMC Medical Genetics
- Vol. 8 (1) , 56
- https://doi.org/10.1186/1471-2350-8-56
Abstract
Type III hyperlipidemia (Type III HLP) is associated with homozygosity for the ε2 allele of the APOE gene. However only about 10% of ε2 homozygotes develop Type III HLP and it is assumed that additional genetic and/or environmental factors are required for its development. Common variants in the LPL gene have been proposed as likely genetic co-factors.Keywords
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