Further Observations in Craniovascular Studies

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Abstract
In recent years considerable attention has been focused on the importance of the extracranial circulation in production of chronic headache. The best available method for studying the external carotid circulation is by the use of displacement transducers connected in series to a calibrator in a multichannel recorder. Using this technique we were able to observe and record the pulsations of the major extracranial arteries, and to test objectively the effect of various drugs on our headache patients. According to pulse volume readings analgesics and sedatives have little effect on the extracranial arterial system. Nicotinic acid may increase amplitude of pulsations in some patients and diminish it in other patients. Rectal administration of ergotamine tartrate produces a vascular response in a shorter space of time than the same medication given orally. The subjective response to a medication is elicited before the evidence can be recorded objectively.

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