XC cell fusion by murine leukemia viruses: Fusion from without
- 1 December 1976
- journal article
- research article
- Published by Springer Nature in Medical Microbiology and Immunology
- Vol. 162 (3-4) , 175-181
- https://doi.org/10.1007/bf02120995
Abstract
Concentrated murine leukemia virus (MuLV) or MuLV producing cells induce XC cell fusion within an hour leading to syncytia formation. While MuLV inactivated by UV irradiation,Β-propiolactone or hydroxylamine treatment still caused cell fusion, Bromelin- or trypsin treated MuLV was no longer able to fuse XC cells. Though sonicated MuLV induced no XC cell fusion, it interfered with cell fusion as caused by untreated MuLV. XC cells infected by diluted MuLV of a titer lower than 1×105 PFU/ml formed no syncytia although they produced MuLV. The call fusion mechanism is discussed.This publication has 30 references indexed in Scilit:
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