8-Hydroxypenillic acid: NMR characteristics and facile formation from 6-aminopenicillanic acid
- 1 June 1994
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 46 (6) , 533-534
- https://doi.org/10.1111/j.2042-7158.1994.tb03848.x
Abstract
High field NMR (1H and 13C) spectral characteristics in D2O of 8-hydroxypenillic acid and 6-aminopenicillanic acid (6-APA)-sodium bicarbonate mixtures are reported. The ready conversion of 6-APA to 8-hydroxypenillic acid is demonstrated.Keywords
This publication has 7 references indexed in Scilit:
- Stereochemical studies of the 4-alkyl-4-arylpiperidine class of opioid ligandMagnetic Resonance in Chemistry, 1989
- Application of 1H nuclear magnetic resonance spectroscopy to the analysis of β-lactam antibiotics and their common degradation productsJournal of Pharmaceutical and Biomedical Analysis, 1987
- Carbon-13 NMR of β-lactam antibiotics and related compoundsMagnetic Resonance in Chemistry, 1986
- 303. Cephalosporanic acids. Part I. Infrared absorption and proton magnetic resonance spectra of cephalosporin and pencillin analoguesJournal of the Chemical Society, 1965
- Action of Carbon Dioxide on 6-Amino-penicillanic AcidNature, 1961
- Identification of a Compound related to 6-Aminopenicillanic Acid, isolated from Culture Media of Penicillium chrysogenumNature, 1961
- REACTION OF 6-AMINOPENICILLANIC ACID WITH CARBON DIOXIDEJournal of the American Chemical Society, 1961