Methionine metabolism in liver diseases
Open Access
- 1 May 2003
- journal article
- research article
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 77 (5) , 1094-1095
- https://doi.org/10.1093/ajcn/77.5.1094
Abstract
The detailed study by Bosy-Westphal et al (1) in this issue of the Journal echoes and significantly extends observations that have been made in numerous laboratories during the past half century. However, despite the clarity of the conclusion that both hypermethioninemia and hyperhomocysteinemia are frequent in patients with chronic liver diseases, the basis for these abnormalities remains obscure.Keywords
This publication has 9 references indexed in Scilit:
- Determinants of hyperhomocysteinemia in patients with chronic liver disease and after orthotopic liver transplantationThe American Journal of Clinical Nutrition, 2003
- Elevated plasma total homocysteine in severe methionine adenosyltransferase I/III deficiencyMetabolism, 2002
- S-Adenosylmethionine, cytokines, and alcoholic liver diseaseAlcohol, 2002
- Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinomaPublished by Elsevier ,2000
- Synthesis of glutathione in response to methionine load in control subjects and in patients with cirrhosisMetabolism, 2000
- Is the Increase in Serum Cystathionine Levels in Patients with Liver Cirrhosis a Consequence of Impaired Homocysteine Transsulfuration at the Level of ?-Cystathionase?Scandinavian Journal of Gastroenterology, 2000
- Induction of TIMP-1 expression in rat hepatic stellate cells and hepatocytes: a new role for homocysteine in liver fibrosisBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1999
- Methionine metabolism in mammalsThe Journal of Nutritional Biochemistry, 1990
- Cystathioninuria and its origin in children with hepatoblastomaThe Journal of Pediatrics, 1980