The bovine rod outer segment guanylate cyclase, ROS-GC, is present in both outer segment and synaptic layers of the retina
- 1 September 1995
- journal article
- Published by Springer Nature in Journal of Molecular Neuroscience
- Vol. 6 (3) , 211-222
- https://doi.org/10.1007/bf02736766
Abstract
Cyclic-GMP, which plays a pivotal role in visual transduction in the vertebrate retina, is synthesized by guanylate cyclase. The purpose of this study was to localize a rod outer segment-derived particulate guanylate cyclase (ROS-GC) to the retina of several species that have different populations of rods and cones. A rabbit antibody was raised against a synthetic peptide, corresponding to the sequence A107-L125 of bovine ROS-GC.Keywords
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