Stress by Heat Shock Induces Massive Down Regulation of Genes and Allows Differential Allelic Expression of the Gal/GalNAc Lectin in Entamoeba histolytica
Open Access
- 1 May 2006
- journal article
- research article
- Published by American Society for Microbiology in Eukaryotic Cell
- Vol. 5 (5) , 871-875
- https://doi.org/10.1128/ec.5.5.871-875.2006
Abstract
Gene expression analysis by microarray assay revealed that when exposed to stress, Entamoeba histolytica exhibits a specific heat shock response, together with a dramatic overall reduction in gene transcription as well as differential allelic expression of key genes participating in virulence, such as the galactose/ N -acetylgalactosamine (Gal/GalNAc) lectin.Keywords
This publication has 21 references indexed in Scilit:
- Intracellular galactose-1-phosphate accumulation leads to environmental stress response in yeast modelMolecular Genetics and Metabolism, 2005
- An unusual surface peroxiredoxin protects invasive Entamoeba histolytica from oxidant attackMolecular and Biochemical Parasitology, 2005
- The FK506-binding protein of the malaria parasite, Plasmodium falciparum, is a FK506-sensitive chaperone with FK506-independent calcineurin-inhibitory activityMolecular and Biochemical Parasitology, 2005
- The genome of the protist parasite Entamoeba histolyticaNature, 2005
- Evolutionary epitopes of Hsp90 and p23: implications for their interactionThe FASEB Journal, 2004
- Stress-Dependent Expression of a Polymorphic, Charged Antigen in the Protozoan Parasite Entamoeba histolyticaInfection and Immunity, 2003
- The Intestinal Protozoan ParasiteEntamoeba histolyticaContains 20 Cysteine Protease Genes, of Which Only a Small Subset Is Expressed during In Vitro CultivationEukaryotic Cell, 2003
- The Bittersweet Interface of Parasite and Host: Lectin-Carbohydrate Interactions During Human Invasion by the ParasiteEntamoeba histolyticaAnnual Review of Microbiology, 2002
- Chaperones get in touch: the Hip-Hop connectionTrends in Biochemical Sciences, 1997
- The cDNA sequence of an abundant Entamoeba histolytica 20-kilodalton protein containing four repetitive domainsMolecular and Biochemical Parasitology, 1993