Hydrazines et hydrazones hétérocycliques. IV. Synthèses de dérivés de l'hydrazine dans la série des imidazo[4,5-d] pyridazinones-4

Abstract
We report the syntheses of 5-alkyl or 5-aryl-3,5-dihydro[4,5-d]imidazo-4-pyridazinones (or the 1,5-dihydro derivatives) from the corresponding diaminopyridazinones. The methylation of 5-alkyl or 5-aryl-2-mercapto-3,5 (or 1,5)-dihydro [4,5-d]imidazo-4-pyridazinones leads to mixtures of 5-alkyl or 5-aryl-1 methyl-2-methylthio-3,5 (1,5)-dihydro[4,5-d]imidazo-4-pyridazinones and 5-alkyl or 5-aryl-3-methyl-2-methylthio-3,5 (or 1,5)-dihydro[4,5-d]imidazo-4-pyridazinones whose structures have been established by the Overhauser effect. These [4,5-d]imidazo-4-pyridazinones are used for the syntheses of hydrazines and hydrozones. The mass spectra of several key intermediates are presented and discussed. [Journal translation]

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