MUC1 Mucin mRNA Expression in Cultured Human Nasal and Bronchial Epithelial Cells
- 1 May 1992
- journal article
- Published by American Thoracic Society in American Journal of Respiratory Cell and Molecular Biology
- Vol. 6 (5) , 516-520
- https://doi.org/10.1165/ajrcmb/6.5.516
Abstract
The MUC1 mucin mRNA, for which the cDNA was previously cloned from human breast and pancreatic tissues, was found to be expressed in nasal and bronchial epithelial cell primary cultures from cystic fibrotic, atopic, and normal individuals. Sequence analysis of cDNA clones from the CF/T43 cystic fibrosis nasal epithelial cell line revealed only insignificant differences in the 3′ untranslated region of the mRNA when compared with the pancreas and breast mucin cDNAs.Keywords
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