Dithiolato-Bridged Dinuclear Iron−Nickel Complexes [Fe(CO)2(CN)2(μ-SCH2CH2CH2S)Ni(S2CNR2)]-Modeling the Active Site of [NiFe] Hydrogenase
- 1 June 2005
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 127 (25) , 8950-8951
- https://doi.org/10.1021/ja051590+
Abstract
[NiFe] hydrogenase, the enzyme of which catalyzes the reversible oxidation of molecular hydrogen to protons and electrons, contains a unique heterodinuclear thiolate-bridged Ni−Fe complex in which the iron center is coordinated by CO and CN. We have synthesized dithiolate-bridged Ni−Fe complexes bearing CO and CN ligands to model the active center of [NiFe] hydrogenase. The Ni−Fe complexes containing a [(CN)2(CO)2Fe(μ-S2)NiS2] framework are the closest yet structural models of [NiFe] hydrogenase.Keywords
This publication has 23 references indexed in Scilit:
- The Influence of Cyanide on the Carbonylation of Iron(II): Synthesis of Fe−SR−CN−CO Centers Related to the Hydrogenase Active SitesJournal of the American Chemical Society, 2001
- Binding of Exogenously Added Carbon Monoxide at the Active Site of the Iron-Only Hydrogenase (CpI) from Clostridium pasteurianum,Biochemistry, 1999
- A 25,000-Year Tropical Climate History from Bolivian Ice CoresScience, 1998
- Biological activition of hydrogenNature, 1997
- Low‐Temperature Complete Combustion of Methane over Mn‐, Co‐, and Fe‐Stabilized ZrO2Angewandte Chemie International Edition in English, 1996
- Structure of the [NiFe] Hydrogenase Active Site: Evidence for Biologically Uncommon Fe LigandsJournal of the American Chemical Society, 1996
- Reactions with Molecular Hydrogen in Microorganisms: Evidence for a Purely Organic Hydrogenation CatalystChemical Reviews, 1996
- Crystal structure of the nickel–iron hydrogenase from Desulfovibrio gigasNature, 1995
- Effect of 17O2 and 13CO on EPR espectra of nickel in hydrogenase from Chromatium vinosumBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1990
- Purification and properties of hydrogenases of different originsBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1968