Molecular Pathways Leading to Cancer Cachexia
- 1 October 2005
- journal article
- review article
- Published by American Physiological Society in Physiology
- Vol. 20 (5) , 340-348
- https://doi.org/10.1152/physiol.00019.2005
Abstract
Loss of body weight in cancer patients strongly influences morbidity and mortality. Recent studies have suggested that both tumor and host factors play a major role in tissue catabolism in cachexia, leading to upregulation of degradative pathways in both skeletal muscle and adipose tissue.Keywords
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