Vasodilatation with Pinacidil
- 1 January 1988
- journal article
- Published by Springer Nature in Drugs
- Vol. 36 (Supplement) , 33-40
- https://doi.org/10.2165/00003495-198800367-00006
Abstract
Pinacidil is a newly developed antihypertensive vasodilator, proposed to belong to the new group of smooth muscle relaxants, the K+ channel openers. The in vitro effects of pinacidil on induced tone,...Keywords
This publication has 14 references indexed in Scilit:
- Role of alpha‐adrenoceptors in constrictor responses of rat, guinea‐pig and rabbit small arteries to neural activation.The Journal of Physiology, 1988
- Similarities in the Mechanism of Action of Two New Vasodilator Drugs: Pinacidil and BRL 34915Journal of Cardiovascular Pharmacology, 1988
- Evidence that the mechanism of the inhibitory action of pinacidil in rat and guinea-pig smooth muscle differs from that of glyceryl trinitrateBritish Journal of Pharmacology, 1987
- Effects of Pinacidil on Serotonin-Induced Contractions and Cyclic Nucleotide Levels in Isolated Rat AortaeJournal of Cardiovascular Pharmacology, 1986
- Atrial natriuretic factor causes specific relaxation of rat renal arcuate arteriesBritish Journal of Pharmacology, 1985
- Effect of Felodipine, a New Dihydropyridine Vasodilator, on Contractile Responses to Potassium, Noradrenaline, and Calcium in Mesenteric Resistance Vessels of the RatJournal of Cardiovascular Pharmacology, 1984
- Role of membrane potential in the response of rat small mesenteric arteries to exogenous noradrenaline stimulation.The Journal of Physiology, 1982
- Prolonged exposure to ouabain eliminates the greater norepinephrine-dependent calcium sensitivity of resistance vessels in spontaneously hypertensive rats.Hypertension, 1981
- Immediate central and peripheral haemodynamic effects of a new vasodilating agent Pinacidil (P1134) in hypertensive manClinical Physiology and Functional Imaging, 1981
- Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats.Circulation Research, 1977