Antibody Inhibitors to von Willebrand Factor Metalloproteinase and Increased Binding of von Willebrand Factor to Platelets in Ticlopidine-Associated Thrombotic Thrombocytopenic Purpura
- 16 May 2000
- journal article
- research article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 132 (10) , 794-799
- https://doi.org/10.7326/0003-4819-132-10-200005160-00005
Abstract
In patients who developed ticlopidine-associated thrombotic thrombocytopenic purpura (TTP), autoantibodies to von Willebrand factor metalloproteinase were formed; this led to the same type of von W... Background: Thrombotic thrombocytopenic purpura (TTP) affects 1 in 1600 to 1 in 5000 patients who receive ticlopidine, but little is known about the pathogenesis of this complication. Objective: To...Keywords
This publication has 19 references indexed in Scilit:
- Thrombotic Thrombocytopenic Purpura Associated With Ticlopidine in the Setting of Coronary Artery Stents and Stroke PreventionArchives of internal medicine (1960), 1999
- Incidence and Clinical Course of Thrombotic Thrombocytopenic Purpura Due to Ticlopidine Following Coronary StentingJAMA, 1999
- Antibodies to von Willebrand Factor–Cleaving Protease in Acute Thrombotic Thrombocytopenic PurpuraNew England Journal of Medicine, 1998
- von Willebrand Factor–Cleaving Protease in Thrombotic Thrombocytopenic Purpura and the Hemolytic–Uremic SyndromeNew England Journal of Medicine, 1998
- A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)The Lancet, 1996
- Thrombotic thrombocytopenic purpura related to ticlopidineThe Lancet, 1991
- Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor.Proceedings of the National Academy of Sciences, 1990
- Immunohistochemistry of vascular lesion in thrombotic thrombocytopenic purpura, with special reference to factor VIII related antigenThrombosis Research, 1985
- Unusually Large Plasma Factor VIII: von Willebrand Factor Multimers in Chronic Relapsing Thrombotic Thrombocytopenic PurpuraNew England Journal of Medicine, 1982
- INCIDENCE OF A POSITIVE DIRECT COOMBS TEST IN PATIENTS ON α-METHYLDOPAThe Lancet, 1966