A family with an inherited translocation involving the no. 4/no. 21 chromosomes.
- 1 December 1975
- journal article
- research article
- Published by BMJ in Journal of Medical Genetics
- Vol. 12 (4) , 408-411
- https://doi.org/10.1136/jmg.12.4.408
Abstract
The clinical and cytogenetic findings of an English family with an unusual chromosomal translocation is reported. The propositus had an unbalanced translocation 4;21 (p11;p12) and had multiple congenital abnormalities. His brother had similar features and probably has the same chromosomal abnormalities. Both his mother and sister have a balanced translocation involving the same chromosomes. His maternal grandmother, although having a normal karyotype, shows an increased number of spontaneous chromosome breaks.This publication has 9 references indexed in Scilit:
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