Antioxidant properties of aTinospora cordifoliapolysaccharide against iron-mediated lipid damage and γ-ray induced protein damage
- 1 June 2002
- journal article
- Published by Taylor & Francis in Redox Report
- Vol. 7 (3) , 137-143
- https://doi.org/10.1179/135100002125000370
Abstract
The antioxidant activity of an arabinogalactan polysaccharide (TSP) isolated from Tinospora cordifolia, an Indian medicinal plant, was studied. The polysaccharide showed good protection against iron-mediated lipid peroxidation of rat brain homogenate as revealed by the thiobarbituric acid reactive substances (TBARS) and lipid hydroperoxide (LOOH) assays. TSP also provided significant protection to protein against gamma-ray induced damage. The protective action can possibly be explained by its very high reactivity towards DPPH, superoxide radicals and the most damaging of radicals, the hydroxyl radical.Keywords
This publication has 24 references indexed in Scilit:
- Formation of a thiobarbituric‐acid‐reactive substance from deoxyribose in the presence of iron saltsPublished by Wiley ,2001
- Free radical scavenging behavior of folic acid: evidence for possible antioxidant activityFree Radical Biology & Medicine, 2001
- Structure−Activity Relationship and Classification of Flavonoids as Inhibitors of Xanthine Oxidase and Superoxide ScavengersJournal of Natural Products, 1998
- [18] Ferrous ion oxidation in presence of ferric ion indicator xylenol orange for measurement of hydroperoxidesPublished by Elsevier ,1994
- Oxidants, antioxidants, and the degenerative diseases of aging.Proceedings of the National Academy of Sciences, 1993
- Invited Review Free Radicals in Disease Processes: A Compilation of Cause and ConsequenceFree Radical Research Communications, 1993
- Reevaluation of assay methods and establishment of kit for superoxide dismutase activityAnalytical Biochemistry, 1984
- Inhibitors of xanthine oxidase from the flowers and buds of Daphne genkwa.CHEMICAL & PHARMACEUTICAL BULLETIN, 1983
- The cooperative interaction between vitamin E and vitamin C in suppression of peroxidation of membrane phospholipidsBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1981
- A simple colorimetric method for the measurement of hydrogen peroxide produced by cells in cultureJournal of Immunological Methods, 1980