Applications of microarray technology in breast cancer research
Open Access
- 1 June 2001
- journal article
- research article
- Published by Springer Nature in Breast Cancer Research
- Vol. 3 (3) , 158-175
- https://doi.org/10.1186/bcr291
Abstract
Microarrays provide a versatile platform for utilizing information from the Human Genome Project to benefit human health. This article reviews the ways in which microarray technology may be used in breast cancer research. Its diverse applications include monitoring chromosome gains and losses, tumour classification, drug discovery and development, DNA resequencing, mutation detection and investigating the mechanism of tumour development.Keywords
This publication has 99 references indexed in Scilit:
- A gene expression database for the molecular pharmacology of cancerNature Genetics, 2000
- Systematic variation in gene expression patterns in human cancer cell linesNature Genetics, 2000
- Distinct types of diffuse large B-cell lymphoma identified by gene expression profilingNature, 2000
- Molecular interactions on microarraysNature Genetics, 1999
- Drug target validation and identification of secondary drug target effects using DNA microarraysNature Medicine, 1998
- Stimulation of B and T Cells Activates Expression of Transcription and Differentiation FactorsBiochemical and Biophysical Research Communications, 1998
- Tissue microarrays for high-throughput molecular profiling of tumor specimensNature Medicine, 1998
- AIB1, a Steroid Receptor Coactivator Amplified in Breast and Ovarian CancerScience, 1997
- Gene-Representing cDNA Clusters Defined by Hybridization of 57,419 Clones from Infant Brain Libraries with Short Oligonucleotide ProbesGenomics, 1996
- Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu OncogeneScience, 1987