Studies on CytochromecOxidase, XI. The Amino-Acid Sequence of Bovine Heart Polypeptide VIc
- 1 January 1985
- journal article
- research article
- Published by Walter de Gruyter GmbH in Biological Chemistry Hoppe-Seyler
- Vol. 366 (1) , 257-264
- https://doi.org/10.1515/bchm3.1985.366.1.257
Abstract
The complete primary structure of the cytoplasmically synthesized polypeptide VIc from beef heart cytochrome c oxidase was determined via isolation and sequencing of overlapping Met and Glu fragments. The protein consists of 73 amino acids (MW 8480). Though the protein contains, from residues 21-40, a hydrophobic sequence interrupted by 1 Lys, it may not penetrate the membrane. A sequence of 33 amino acids highly homologous to the C-terminal part of VIc was translated from a c[complementary]DNA clone of a nuclear coded subunit of the enzyme from rat liver. The function of this component of the terminal oxidase is yet unknown.This publication has 14 references indexed in Scilit:
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