APPENDICITIS is still a very prevalent disease, and there are still many problems in the treatment which have not been conclusively solved. The accumulation and the reporting of the experience in the treatment of adequately large groups of patients will record the trend of thought and management as well as assist in forming conclusions helpful in the treatment of appendicitis. It is for that purpose that this report is made concerning the treatment of appendicitis in St. Joseph's Mercy Hospital, Ann Arbor, Mich., during the ten year period 1935 through 1944. This period was chosen because the first five years represent the introduction of intravenous fluids, continuous gastric suction, more frequent blood transfusions and certain changes in surgical technic. The second five years had the added advantages of the sulfonamide compounds, but penicillin was not yet used. These two periods lend themselves to certain comparisons as to methods of treatment