Four-year follow-up of a case of acute multiple sclerosis of the Marburg type
- 1 March 1997
- journal article
- case report
- Published by Springer Nature in The Italian Journal of Neurological Sciences
- Vol. 18 (3) , 163-166
- https://doi.org/10.1007/bf02048485
Abstract
We describe the clinical course, treatment and magnetic resonance findings during a four-year follow-up of a patient with acute multiple sclerosis of the Marburg type, treated with steroid and mannitol therapy, who survived the first bout. Although the course of the disease was clinically indistinguishable from relapsing-remitting multiple sclerosis, our case was characterized by peculiar features. These included the need for protracted steroid therapy and the remarkable tendency of MRI lesions to resolve completely. Descriviamo il decorso clinico, la terapia e i quadri di risonanza magnetica durante un periodo di quattro anni di una paziente affetta da sclerosi multipla acuta tipo Marburg, trattata con steroidi e mannitolo, che sopravvisse al primo attacco. Sebbene il decorso clinico era simile ad una forma remittente di sclerosi multipla, il nostro caso si caratterizzava per la necessità di una protratta terapia steroidea e per la tendenza delle lesioni presenti alla risonanza magnetica di risolversi completamente.Keywords
This publication has 11 references indexed in Scilit:
- Limited duration of the effect of methylprednisolone on changes on MRI in multiple sclerosisNeuroradiology, 1994
- Fulminant multiple sclerosis.1992
- CSF myelin basic protein, IgG and IgM levels in 101 MS patients before and after treatment with high-dose intravenous methylprednisoloneActa Neurologica Scandinavica, 1992
- Fulminant monophasic multiple sclerosis, Marburg's type.Journal of Neurology, Neurosurgery & Psychiatry, 1990
- ACUTE DISSEMINATED ENCEPHALOMYELITISBrain, 1990
- Primary CNS lymphomaNeurology, 1990
- PRIMARY INTRACRANIAL CNS LYMPHOMA - MR MANIFESTATIONS1989
- Malignant monophasic multiple sclerosis or “Marburg's disease"Neurology, 1988
- New diagnostic criteria for multiple sclerosis: Guidelines for research protocolsAnnals of Neurology, 1983