The Pneumococcal Pilus Predicts the Absence ofStaphylococcus aureusCo‐Colonization in Pneumococcal Carriers

Abstract
The determinants of the negative association between Streptococcus pneumoniae and Stapylococcus aureus colonization are unknown. In this matched case-control study, the odds of co-colonization with S. aureus were significantly lower for individuals carrying a piliated versus a nonpiliated S. pneumoniae strain, suggesting the pilus may be a determinant of the negative association.

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