OESTRADIOL-17β UPTAKE IN VITRO INTO THE NUCLEI OF ENDOMETRIUM FROM DIFFERENT REGIONS OF THE HUMAN UTERUS

1 February 1975

journal article
Published by Oxford University Press (OUP) in Acta Endocrinologica

Vol. 78 (2) , 353-363
https://doi.org/10.1530/acta.0.0780353

Abstract

Specimens of endometrium from the vault, body and lower body regions of the same human uteri were incubated separately for 30 min in vitro in the presence of 1–6 × 10⁻⁹m ³H-oestradiol. Uptake into the nuclei was variable but in general the vault region endometrium was least active in nuclear accumulation of the hormone, especially in secretory phase endometrium. This suggests that intra-uterine variations found in oestradiol uptake in vivo are due to regional differences in the state of the tissue itself.

Keywords

ENDOMETRIUM
UPTAKE
NUCLEI
OESTRADIOL
REGIONAL DIFFERENCES
SUP
INCUBATED
TISSUE
HORMONE
17Β

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