The Perinatal Group B Streptococcal Problem: More Questions Than Answers

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Abstract
IT was not until 1938, five years after Lancefield introduced streptococcal precipitin typing, that streptococci belonging to Group B were related causally to severe human disease.1 That Streptococcus agalactiae could be an important cause of perinatal morbidity and mortality was documented by Hood and his associates2 in 1961 and by Eickhoff and his co-workers3 in 1964. Since 1971, Group B beta-hemolytic streptococcal infection in neonates has become a subject of increasing attention and concern largely because in many centers they are now the organism associated most frequently with neonatal septicemia.The epidemiology and pathogenesis of Group B streptococcal infection in . . .