A STUDY OF THE BLOOD IODINE IN CHILDHOOD

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Abstract
The blood I of 100 normal children from birth to 13 yrs. was detd. by the Trevorrow-Fashena acid digestion method. In 21 infants under 24 hrs. of age the blood I range was 1-11 y per 100 cc. with an average of 4.7 [plus or minus] 0.33 [gamma]; the remaining subjects showed a range of 3-12 [gamma] % with an av. of 6.6 [plus or minus] 0.15 [gamma]. The blood I increased with age in the first 2-3 weeks of life but showed no other consistent variation with age. The blood I of subjects on a high-I diet was not consistently higher than that of a similar group on a low-I feeding. From 2 to 3 hrs. after an I-rich meal a temporary alimentary iodemia was observed irregularly. No significant changes in blood I were observed between the 2 sexes, in febrile states, or with change of season. Patients with known thyroid disease frequently exhibited normal blood iodine values; such determinations, therefore, have little absolute diagnostic significance.

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