Synthetic Scotophobin in Goldfish: Specificity and Effect on Learning

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Abstract
Synthetic rat scotophobin was injected intracranially into common goldfish ( Carassius auratus ) which were then trained to avoid light or dark. The substance interacts with the learning process in goldfish in an apparently specific way, facilitating the acquisition of dark avoidance, a task homologous with that acquired by rats from which the natural peptide was isolated, while inhibiting acquisition of light avoidance.