CHOROID-PLEXUS PAPILLOMA .1. PROOF OF CEREBROSPINAL-FLUID OVERPRODUCTION

  • 1 January 1976
    • journal article
    • research article
    • Vol. 2  (5) , 273-289
Abstract
Utilizing a ventricular perfusion technique, the rate of CSF formation was determined in a 2 yr old child before and after removal of a 74 g choroid plexus papilloma from the left lateral ventricle. Preoperatively the CSF formation rate was 1.05 .+-. SD 0.01 ml/min (1656 ml/day). Postoperatively the CSF formation rate was reduced 5-fold to 0.20 .+-. SD 0.01 ml/min (288 ml/day). Whereas these data are regarded as conclusive evidence of CSF overproduction by a choroid plexus papilloma, the pathogenesis of generalized ventricular enlargement in this case was due in part to obstruction of the subarachnoid pathways.

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