Studies on fatty acid-binding proteins. The diurnal variation shown by rat liver fatty acid-binding protein
- 15 March 1987
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 242 (3) , 913-917
- https://doi.org/10.1042/bj2420913
Abstract
The concentration of fatty acid-binding protein in rat liver was examined by SDS/polyacrylamide-gel electrophoresis, by Western blotting and by quantifying the fluorescence enhancement achieved on the binding of the fluorescent probe 11-(dansylamino)undecanoic acid. A 2-3-fold increase in the concentration of this protein produced by treatment of rats with the peroxisome proliferator tiadenol was readily detected; however, only a small variation in the concentration of the protein due to a diurnal rhythm was observed. This result contradicts the 7-10-fold variation previously reported for this protein [Hargis, Olson, Clarke and Dempsey (1986) J. Biol. Chem. 261, 1988-1991].This publication has 17 references indexed in Scilit:
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