Novel Glucoalkaloids from Rauwolfia Cell Cultures – Acetylrauglucine and Related Glucosides
Open Access
- 1 August 1988
- journal article
- research article
- Published by Walter de Gruyter GmbH in Zeitschrift für Naturforschung C
- Vol. 43 (7-8) , 479-484
- https://doi.org/10.1515/znc-1988-7-801
Abstract
From cell suspension cultures of Rauwolfia serpentina grown in an optimized production medium for the glucoalkaloid raucaffricine, a novel glucoalkaloid was isolated and identified as 17-O-acetyl-21-O-.beta.-D-glucopyranosyl-ajmaline (acetylrauglucine). This alkaloid is formed in very small amounts (> 5 .times. 10-4%). The biogenetically related N.alpha.-demethylated base (acetyl-nor-rauglucine) and the deacetyl product rauglucine have also been detected in culture extracts. In addition 21(R)-(.beta.-D-glucopyranosyl)-hydroxy-sarpagan-17-al has been isolated and identified as an artifact which originates from raucaffricine.Keywords
This publication has 8 references indexed in Scilit:
- Purification of Secologanin fromLonicera tataricaExtracts Using RLCCPlanta Medica, 1987
- Characterization of 2β(R)-17-O-AcetylajmaIan: Acetylesterase — a Specific Enzyme Involved in the Biosynthesis of the Rauwolfia Alkaloid AjmalineZeitschrift für Naturforschung C, 1987
- Ajmalicidine an alkaloid from Rauwolfia serpentinaPhytochemistry, 1987
- Isolation and structure of a new alkaloid from rauwolfia serpentina benthTetrahedron, 1985
- Isolation and Structure of a New Alkaloid from the Roots of Rauwolfia Serpentina BenthHETEROCYCLES, 1985
- Structure Revision of the Rauwolfia Alkaloid RaucaffricineHelvetica Chimica Acta, 1984
- New Saponins from Phytolacca dodecandra l'HERITHelvetica Chimica Acta, 1984
- Alkaloid Distribution in Some African Rauvolfia SpeciesPlanta Medica, 1983