Ultrastructural Alteration of Rat Cardiac Myofibrils Caused by a Myosin-Cleaving Protease1
- 1 July 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Biochemistry
- Vol. 88 (3) , 877-881
- https://doi.org/10.1093/oxfordjournals.jbchem.a133042
Abstract
Incubation of rat cardiac myofibrils with a myosin-cleaving protease in the presence of EDTA at 25°C caused removal of Z- and M-lines, accompanied by myofibril fragmentation. When rat cardiac muscle I-Z-I brushes were subjected to proteolysis, the protein components with the molecular weights of 55,000 and 50,000 were degraded by the protease. Ca2+ was not required for the ultrastructural alterations of myofibrils caused by the protease action.Keywords
This publication has 1 reference indexed in Scilit:
- MYOFIBRIL FRAGMENTATION AND SHEAR RESISTANCE OF THREE BOVINE MUSCLES DURING POSTMORTEM STORAGEJournal of Food Science, 1976