CLINICAL AND ENDOCRINOLOGIC EXAMINATIONS ABOUT THERAPY OF CLIMACTERIC SYMPTOMS FOLLOWING HYSTERECTOMY WITH REMAINING OVARIES

  • 1 January 1988
    • journal article
    • research article
    • Vol. 110  (10) , 611-618
Abstract
60 hysterectomized patients under 40 years old, who all had at least one intact ovary and still complained of climacteric symptoms, were treated with estriol, conjugated estrogens, estrogen-gestagen sequential therapy or an extract from cimicifuga racemosa after randomized distribution into 4 equal groups. Therapy was controlled after 4, 8, 12 and 24 weeks with a modified Kupperman-Index that also included trophic disorders of the genitals, and also by serum-FSH and -LH measurements. In all groups, the modified Kupperman-Index became significantly lower, the parallel decrease of gonadotropins could not be confirmed statistically, however. There were no significant differences between groups concerning therapy success.

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