Abstract
A method is described for the determination of the direct mean systemic blood pressure in the femoral artery of the unanesthetized rabbit. Weekly blood pressures of 24 rabbits, for 3 successive weeks, and of 6 other rabbits, for 12 weeks, are given. The mean direct femoral blood pressure of the individual rabbit is remarkably uniform and the variation among different rabbits is not great. Production of persistent renal hypertension, unaccompanied by significant impairment of renal excretory function, is described and illustrated.

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