NMR studies of chromomycins, olivomycins, and their derivatives.
- 1 January 1988
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 41 (1) , 53-67
- https://doi.org/10.7164/antibiotics.41.53
Abstract
Detailed studies on the 13C and 1H NMR spectra of chromomycins A2 and A3, olivomycins A and B, and their derivatives clarified the assignment of many signals which had been unassigned or erronously reported in the literature. The revised assignments for chromomycin A3 and olivomycin A include the assignment of a key 13C signal used to discuss the saccharide linkage in question. Structure analyses based on the revised assignments support the .alpha.,1 .fwdarw. 3 bond between components of the disaccharide moiety in the molecules. Some general information useful for structure analysis of saccharides is also reported.This publication has 4 references indexed in Scilit:
- New aureolic acid antibiotics. II. Structure determination.The Journal of Antibiotics, 1988
- New aureolic acid antibiotics. I. Screening, isolation, characterization and biological properties.The Journal of Antibiotics, 1988
- Studies on the structure of olivomycin a and mithramycin by 1H and 13C nuclear magnetic resonance spectroscopyTetrahedron, 1981
- Preparation and antitumor activity of olivomycin A analogsJournal of Medicinal Chemistry, 1980