Chemistry and Pharmacology ofGentiana lactea
- 31 May 1988
- journal article
- research article
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 54 (03) , 219-221
- https://doi.org/10.1055/s-2006-962408
Abstract
Flavonoids, secoiridoids, and xanthones of Gentiana lactea (Gentianaceae) were investigated and 14 compounds were identified, among these the previously undescribed 2-C-β-D-glucopyranosyl-1,3,7-trihydroxyxanthone (neolancerin). The known constituents of G. lactea include bellidifolin, bellidifolin-8-O-glucoside, deacetylcentapicrin, demethylbellidifolin, demethylbellidifolin-8-O-glucoside, gentiopicrin, isoorientin, isovitexin, loganic acid, mangiferin, swerchirin, sweroside, and swertiamarin. Xanthones with 1,3,5,8-substitution patterns were tested for inhibition of monoamino oxidase. Bellidifolin (1,5,8-trihydroxy-3-methoxyxanthone) was found to be a strong and selective inhibitor of MAO A in vitro.This publication has 13 references indexed in Scilit:
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