Vitamin K and the Oral Anticoagulant Drugs
- 1 February 1976
- journal article
- review article
- Published by Annual Reviews in Annual Review of Medicine
- Vol. 27 (1) , 245-261
- https://doi.org/10.1146/annurev.me.27.020176.001333
Abstract
The evolution of vitamin K, from a dietary deficiency in birds to a postribosomal modifier of prothrombin in man, has been a fascinating scientific saga. Its antivitamin, the oral anticoagulant drugs, has been a powerful probe both of vitamin K action and of drug interactions. These agents have emerged from a limbo of clinical therapeutics to become a light of human pharmacology.Keywords
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