Neuron-specific enolase-positive rosettes in nephroblastoma: A possible diagnostic pitfall in aspiration cytology
- 1 March 1987
- journal article
- case report
- Published by Wiley in Diagnostic Cytopathology
- Vol. 3 (1) , 74-76
- https://doi.org/10.1002/dc.2840030114
Abstract
Neuron-specific enolase-positive cells, some arranged in rosettes, were identified in smears obtained in fine-needle aspiration of a left retroperitoneal tumor found in a 3-yr-old boy. Nephrectomy showed a typical nephroblastoma with a prominent blastemic component revealing a positive reaction for neuron-specific enolase in blastemic and tubular components. Neuron-specific, enolase-positive, small malignant cells are not diagnostic of neuroblastoma when coming from a tumor of the retroperitoneum even if rosettes are present.Keywords
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