Expression, localization and potential physiological significance of alcohol dehydrogenase in the gastrointestinal tract
Open Access
- 27 May 2003
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 270 (12) , 2652-2662
- https://doi.org/10.1046/j.1432-1033.2003.03642.x
Abstract
ADH1 and ADH4 are the major alcohol dehydrogenases (ADH) in ethanol and retinol oxidation. ADH activity and protein expression were investigated in rat gastrointestinal tissue homogenates by enzymati...Keywords
This publication has 65 references indexed in Scilit:
- Distinct Retinoid Metabolic Functions for Alcohol Dehydrogenase Genes Adh1 and Adh4 in Protection against Vitamin A Toxicity or Deficiency Revealed in Double Null Mutant MiceJournal of Biological Chemistry, 2002
- Alcohol and RetinoidsAlcohol, Clinical and Experimental Research, 2001
- Expression pattern and localization of β,β-carotene 15,15′-dioxygenase in different tissuesBiochemical Journal, 2001
- Effect of Cellular Retinol-Binding Protein on Retinol Oxidation by Human Class IV Retinol/Alcohol Dehydrogenase and Inhibition by EthanolBiochemical and Biophysical Research Communications, 1998
- Retinoids, ω‐hydroxyfatty acids and cytotoxic aldehydes as physiological substrates, and H2‐receptor antagonists as pharmacological inhibitors, of human class IV alcohol dehydrogenaseFEBS Letters, 1998
- Alcohol dehydrogenase in human tissues: localisation of transcripts coding for five classes of the enzymeFEBS Letters, 1996
- Expression and Kinetic Characterization of Recombinant Human Stomach Alcohol DehydrogenaseJournal of Biological Chemistry, 1995
- Distribution of alcohol and sorbitol dehydrogenasesEuropean Journal of Biochemistry, 1993
- The contribution of the stomach to ethanol oxidation in the ratLife Sciences, 1987
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976