CONTRIBUTIONS TO THE PHYSIOLOGY OF THE STOMACH

Open Access

19 September 1925

journal article
research article
Published by American Medical Association (AMA) in JAMA

Vol. 85 (12) , 877-880
https://doi.org/10.1001/jama.1925.02670120015005

Abstract

When my colleagues and I began the study of gastric secretion, it was generally taught that gastric secretion following a meal was caused (a) psychically by the sight, smell and taste of food, and (b) chemically by the local action in the stomach of specific substances in or derived from food and by a hormone, gastrin, which was elaborated by the contact of food substances with the gastric mucosa. Evidence that has been accumulating during the last five years has made it necessary for us to change some of our views and to present a new classification of the factors concerned in the genesis of gastric secretion. THE CEPHALIC PHASE OF GASTRIC SECRETION The observations and experiments of Bidder and Schmidt,¹Richet,²Pawlow,³Carlson⁴and others have demonstrated unequivocally that the sight, smell and taste of food cause the gastric glands to secrete, provided the person

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