THE EFFECT OF AN ANTERIOR HYPOPHYSEAL EXTRACT UPON THE SERUM CALCIUM AND PHOSPHORUS

Abstract
Each of 19 guinea pigs was injected intra-peritoneally daily for 9 days with 1 cc. of alkaline extract of the ant. hypophysis. 15 guinea pigs on an identical diet were reserved for controls. The extract-treated animals showed a significantly elevated serum-Ca level as compared with the untreated controls. The serum phosphates were not affected by these injections. These data, in addition to other available evidence, indicate that the ant. hypophyseal extract exhibited a para-thyreotropic activitv.

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