Complete remission of paraneoplastic sensorimotor neuropathy: A case associated with small‐cell lung cancer responsive to chemotherapy, plasma exchange, and radiotherapy

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Abstract
A 61‐year‐old man was found to have small‐cell lung cancer following a 1‐year history of a progressive peripheral sensorimotor neuropathy. The neuropathy initially improved following chemotherapy, but subsequently progressed to the point of respiratory failure. Treatment with plasma exchange, additional chemotherapy, and radiotherapy resulted in a sustained complete tumor remission and neurologic recovery. The role of plasma exchange is unclear, but its use should be considered in cases of severe sensorimotor neuropathy unresponsive to antineoplastic treatment.