A Case of Uric Acid Renal Stone with Hypouricemia Caused by Tubular Reabsorptive Defect of Uric Acid
- 1 December 1976
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 116 (6) , 690-692
- https://doi.org/10.1016/s0022-5347(17)58973-9
Abstract
A 60 yr old man had a uric acid [UA] stone in the kidney and laboratory findings of hypouricemia (1.1 mg%) and increased UA clearance [C] (43 ml/min per 1.73 m2). CUA exceeded the endogenous creatinine C after administration of pyrazinamide, an inhibitor of renal tubular secretion of UA. The patient had a complete defective mechanism for UA reabsorption, resulting in hyperuricuria and the formation of the UA stone.This publication has 10 references indexed in Scilit:
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