Determination of Fluorocarbon Propellants in Blood and Animal Tissue

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Abstract
A liexane extraction procedure was evaluated for determining several common fluorocarbon propellants—dichlorodifluoromethane, trichlorofluoromethane, and 1,2-dichlorotetrafluoroethane—in blood. An analysis of sample headspace was also evaluated for determining chloropentafluoroethane in blood. Both procedures involved analysis by gas chromatography using electron capture detection. The widely used hexane extraction (with analysis by gas chromatography) procedure for determining part-per-million levels of volatile halocarbons in tissue was evaluated by a combination of radiochemical and gas chromatogiraphic techniques. The data suggest that hexane extraction gives significantly low results.

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