Studies on the Transfer of Human Delayed-Type Hypersensitivity
Open Access
- 1 September 1966
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 97 (3) , 407-420
- https://doi.org/10.4049/jimmunol.97.3.407
Abstract
Summary: Two fractions from tuberculin hypersensitive human white blood cells have been found capable of transferring tuberculin delayed hypersensitivity. One of these (C′-5) is a polynucleotide containing adenine, guanine and cytosine, but no uracil. The second transfer factor is contained in a larger molecular weight (A′) fraction found to have γG-globulin and other globulin and probably α1 lipoprotein as well as ribose indicating RNA. A fraction containing macroglobulin was unable to transfer delayed hypersensitivity.Keywords
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