Monte Carlo simulation of DNA electrophoresis
- 1 January 1989
- journal article
- review article
- Published by Wiley in Electrophoresis
- Vol. 10 (5-6) , 442-446
- https://doi.org/10.1002/elps.1150100522
Abstract
This paper describes an attempt to study the electrophoresis mobility of a DNA molecule in a gel by means of a Monte Carlo simulation. We find that the electrophoresis mobility μ can be well described by the empirical equation μ = κ1/N + κ2E2 with N being the number of monomers of the model chain and E being the applied field. For small E the data can merge into the linear response result μ = κ1/N. The paper also discusses necessary extensions of the present approach.Keywords
This publication has 16 references indexed in Scilit:
- Quantitative analysis of the three regimes of DNA electrophoresis in agarose gelsBiopolymers, 1988
- Criticisms of the recently proposed analysis and methods of ‘thermoviscoelasticity’Polymer, 1988
- A trapped polymer chain in random porous mediaThe Journal of Chemical Physics, 1987
- On the stretching of DNA in the reptation theories of gel electrophoresisBiopolymers, 1987
- Diffusion in disordered mediaAdvances in Physics, 1987
- Diffusion of DNA in a gel under an intermittent electric fieldBiopolymers, 1986
- Electrophoresis in strong fieldsPhysical Review A, 1986
- Mobility of DNA in gel electrophoresisBiopolymers, 1982
- Why does the electrophoretic mobility of DNA in gels vary with the length of the molecule?Biopolymers, 1982
- Thermodynamics and equilibrium sedimentation analysis of the close approach of DNA molecules and a molecular ordering transitionBiopolymers, 1981