Adenovirus-Mediated Gene Transfer of Human Platelet-Activating Factor–Acetylhydrolase Prevents Injury-Induced Neointima Formation and Reduces Spontaneous Atherosclerosis in Apolipoprotein E–Deficient Mice
- 22 May 2001
- journal article
- other
- Published by Wolters Kluwer Health in Circulation
- Vol. 103 (20) , 2495-2500
- https://doi.org/10.1161/01.cir.103.20.2495
Abstract
Background—Atherosclerosis is characterized by an early inflammatory response involving proinflammatory mediators such as platelet-activating factor (PAF)-like phospholipids, which are inactivated ...Keywords
This publication has 24 references indexed in Scilit:
- Inorganic and organic phosphate measurements in the nanomolar rangePublished by Elsevier ,2004
- Sustained Expression of Human Apolipoprotein A-I after Adenoviral Gene Transfer in C57BL/6 Mice: Role of Apolipoprotein A-I Promoter, Apolipoprotein A-I Introns, and Human Apolipoprotein E EnhancerHuman Gene Therapy, 2000
- The role of oxidized lipoproteins in atherogenesisPublished by Elsevier ,1999
- Substitution of the carboxyl-terminal domain of apo AI with apo AII sequences restores the potential of HDL to reduce the progression of atherosclerosis in apo E knockout mice.Journal of Clinical Investigation, 1998
- Oxidatively modified LDL contains phospholipids with platelet-activating factor-like activity and stimulates the growth of smooth muscle cells.Journal of Clinical Investigation, 1995
- Oxygen radicals inhibit human plasma acetylhydrolase, the enzyme that catabolizes platelet-activating factor.Journal of Clinical Investigation, 1994
- The pathogenesis of atherosclerosis: a perspective for the 1990sNature, 1993
- Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells.Proceedings of the National Academy of Sciences, 1992
- Quantitation of plasma free cholesterol and cholesteryl esters by high performance liquid chromatography Study of a normal populationAtherosclerosis, 1989
- Effect of harvesting methods, growth conditions and growth phase on diacylglycerol levels in cultured human adherent cellsBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1988