EFFECTS OF SHEEP AND YOUNG CALF PINEAL EXTRACTS AND CONTINUOUS LIGHT ON THE PINEAL GLAND, THE GONADS AND THE OESTROUS CYCLE OF THE RAT

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Abstract
Injections of a water-soluble pineal extract into young female rats kept under a normal light/dark rhythm caused a relatively high frequency of abnormal nuclei in the pineal gland. This nuclear response suggests a secretory activity in normal pinealocytes. No effect of the pineal extract on the reproductive system was observed. In females exposed to continuous light, neither the water-soluble extract nor the acetone-soluble pineal material interfered with the light induced alterations in the oestrous cycle, the uterine and ovarian weights, the condition of the pineal nuclei and the quantity of pineal lipids.

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