Rho-Regulatory Proteins in Breast Cancer Cell Motility and Invasion
- 1 March 2004
- journal article
- review article
- Published by Springer Nature in Breast Cancer Research and Treatment
- Vol. 84 (1) , 49-60
- https://doi.org/10.1023/b:brea.0000018424.43445.f3
Abstract
The importance of the Rho-GTPases in cancer progression, particularly in the area of metastasis, is becoming increasingly evident. This review will provide an overview of the role of the Rho-regulatory proteins in breast cancer metastatis.Keywords
This publication has 121 references indexed in Scilit:
- Distinct Role of Phosphatidylinositol 3-Kinase and Rho Family GTPases in Vav3-induced Cell Transformation, Cell Motility, and Morphological ChangesPublished by Elsevier ,2002
- Cooperativity between the Ras-ERK and Rho-Rho Kinase Pathways in Urokinase-type Plasminogen Activator-stimulated Cell MigrationJournal of Biological Chemistry, 2002
- Untying the Gordian Knot of CytokinesisThe Journal of cell biology, 2000
- RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasionOncogene, 2000
- Evidence for a Novel RasGAP-Associated Protein of 105 kDa in both Mature Trophoblasts and Differentiating Choriocarcinoma CellsBiochemical and Biophysical Research Communications, 1999
- Genomic Structure and Assignment of theRhoH/TTFSmall GTPase Gene (ARHH) to 4p13 byin SituHybridizationGenomics, 1997
- p190-B, a New Member of the Rho GAP Family, and Rho Are Induced to Cluster after Integrin Cross-linkingJournal of Biological Chemistry, 1995
- Specific chromosomal defects associated with metastatic potential in K-1735 melanoma clones: Involvement of chromosomes 4 and 14Cancer Genetics and Cytogenetics, 1991
- rho Gene amplification and malignant transformationBiochemical and Biophysical Research Communications, 1990
- The rho gene product expressed in E. Coli is a substrate of botulinum ADP-ribosyltransferase C3Biochemical and Biophysical Research Communications, 1989