Predictive testing for Huntington disease: I. Description of a pilot project in British Columbia
- 1 February 1989
- journal article
- research article
- Published by Wiley in American Journal of Medical Genetics
- Vol. 32 (2) , 211-216
- https://doi.org/10.1002/ajmg.1320320214
Abstract
The discovery of DNA markers linked to the gene causing Huntington disease (HD) has allowed the development of predictive testing programs for persons at‐risk. A pilot program was established in British Columbia in November 1986. Ninetyfive persons are currently enrolled. The major objective of this project is to introduce and evaluate a protocol for the delivery of test results to persons at‐risk for HD. The criteria for entry and details of the psychosocial assessment before and after receiving a modified risk are presented. The guidelines that are developed from this project will have major applications for predictive testing programs for other late onset autosomal dominant disorders.Keywords
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