Cyclic tetrapeptides of glycine or alanine combined with sarcosine; the co-existence of neutral and protonated species

Abstract
All combinations between glycine and sarcosine, and between alanine and sarcosine, in a cyclic tetrapeptide have been synthesized; when n.m.r. spectroscopy can be applied, the same cis,trans,cis,trans-conformation, neutral or protonated, is indicated, as long as α-methyl groups do not give rise to steric hindrance.

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