RESULTS OF THE ROYAL-MARSDEN-HOSPITAL 2ND SOFT-TISSUE SARCOMA SCHEDULE (STS-II) CHEMOTHERAPY REGIMEN IN THE MANAGEMENT OF ADVANCED SARCOMA

  • 1 January 1980
    • journal article
    • research article
    • Vol. 64  (4-5) , 689-692
Abstract
Patients (48) with advanced soft tissue sarcoma were treated with a 5-drug combination regimen consisting of vincristine, actinomycin D and cyclophosphamide (Day 1) followed by doxorubicin and an infusion of methotrexate (Day 22). Thirty-seven of the 48 patients were fully evaluable. Of the 37 evaluable patients, 2 achieved a complete remission and 3 achieved a partial remission, with an overall response rate of 13.5%. These results compare unfavorably with previously reported series from this and other centers; the regimen has now been superseded.

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