Synovial cytokine mRNA expression during arthritis triggered by CpG motifs of bacterial DNA
Open Access
- 27 October 2000
- journal article
- research article
- Published by Springer Nature in Arthritis Research & Therapy
- Vol. 3 (1) , 48-53
- https://doi.org/10.1186/ar139
Abstract
Our results show that cytokines derived from macrophages play an important role in pathogenesis of arthritis triggered by CpG oligodinucleotide (CpG ODN). IL-12 is in this respect an important immunomodulator during the development of joint inflammation.Keywords
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